Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB(2) Receptor

Activation of CB(2) has been demonstrated to induce directed immune cell migration. However, the ability of CB2 to act as a chemoattractant receptor in macrophages remains largely unexplored. Using a real-time chemotaxis assay and a panel of chemically diverse and widely used CB(2) agonists, we set...

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Publicat a:Sci Rep
Autors principals: Taylor, Lewis, Christou, Ivy, Kapellos, Theodore S., Buchan, Alice, Brodermann, Maximillian H., Gianella-Borradori, Matteo, Russell, Angela, Iqbal, Asif J., Greaves, David R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451551/
https://ncbi.nlm.nih.gov/pubmed/26033291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10682
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