Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity

BACKGROUND & AIMS: Bile acids (BAs) are major regulators of hepatic BA and lipid metabolism but their mechanisms of action in non-alcoholic fatty liver disease (NAFLD) are still poorly understood. Here we aimed to explore the molecular and biochemical mechanisms of ursodeoxycholic acid (UDCA) in...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Mueller, Michaela, Thorell, Anders, Claudel, Thierry, Jha, Pooja, Koefeler, Harald, Lackner, Carolin, Hoesel, Bastian, Fauler, Guenter, Stojakovic, Tatjana, Einarsson, Curt, Marschall, Hanns-Ulrich, Trauner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451470/
https://ncbi.nlm.nih.gov/pubmed/25617503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.12.034
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