Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells

Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor mainly caused by mutations in the RET proto-oncogene. For therapy of advanced MTC, the Food and Drug Administration recently approved vandetanib and cabozantinib, the tyrosine kinase inhibitors targeting RET, vascular endothelial growth fac...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Starenki, Dmytro, Hong, Seung-Keun, Lloyd, Ricardo V., Park, Jong-In
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451452/
https://ncbi.nlm.nih.gov/pubmed/25435367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.392
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