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A potent and selective inhibitor for the UBLCP1 proteasome phosphatase

The ubiquitin-like domain-containing C-terminal domain phosphatase 1 (UBLCP1) has been implicated as a negative regulator of the proteasome, a key mediator in the ubiquitin-dependent protein degradation. Small molecule inhibitors that block UBLCP1 activity would be valuable as research tools and pot...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem
Main Authors: He, Yantao, Guo, Xing, Yu, Zhi-Hong, Wu, Li, Gunawan, Andrea M., Zhang, Yan, Dixon, Jack E., Zhang, Zhong-Yin
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451428/
https://ncbi.nlm.nih.gov/pubmed/25907364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.03.066
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