A Protective Role For Club Cell Secretory Protein-16 (CC16) In The Development of Chronic Obstructive Pulmonary Disease (COPD)

RATIONALE: Club cell secretory protein-16 (CC16) is the major secreted product of airway Club cells, but its role in the pathogenesis of COPD is unclear. We measured CC16 airway expression in humans with and without COPD and CC16 function in a cigarette smoke (CS)-induced COPD mice model. METHODS: A...

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Publicado no:Eur Respir J
Main Authors: Laucho-Contreras, Maria E., Polverino, Francesca, Gupta, Kushagra, Taylor, Katherine L., Kelly, Emer, Pinto-Plata, Victor, Divo, Miguel, Afshaq, Naveed, Petersen, Hans, Stripp, Barry, Pilon, Aprile L., Tesfaigzi, Yohannes, Celli, Bartolome R., Owen, Caroline A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451404/
https://ncbi.nlm.nih.gov/pubmed/25700379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00134214
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