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Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling

The most severe complication of influenza is viral pneumonia, which can lead to the acute respiratory distress syndrome. Alveolar epithelial cells (AECs) are the first cells that influenza virus encounters upon entering the alveolus. Infected epithelial cells produce cytokines that attract and activ...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Ito, Yoko, Correll, Kelly, Zemans, Rachel L., Leslie, Christina C., Murphy, Robert C., Mason, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451400/
https://ncbi.nlm.nih.gov/pubmed/26033355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00290.2014
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