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Aortic perivascular adipose-derived interleukin-6 contributes to arterial stiffness in low-density lipoprotein receptor deficient mice

We tested the hypothesis that aortic perivascular adipose tissue (PVAT) from young low-density lipoprotein receptor-deficient (LDLr(−/−)) mice promotes aortic stiffness and remodeling, which would be mediated by greater PVAT-derived IL-6 secretion. Arterial stiffness was assessed by aortic pulse wav...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Heart Circ Physiol
Prif Awduron: Du, Bing, Ouyang, An, Eng, Jason S., Fleenor, Bradley S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451307/
https://ncbi.nlm.nih.gov/pubmed/25840831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00712.2014
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