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Superoxide signaling in perivascular adipose tissue promotes age-related artery stiffness

We tested the hypothesis that superoxide signaling within aortic perivascular adipose tissue (PVAT) contributes to large elastic artery stiffening in old mice. Young (4–6 months), old (26–28 months), and old treated with 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPOL), a superoxide scavenger...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Fleenor, Bradley S, Eng, Jason S, Sindler, Amy L, Pham, Bryant T, Kloor, Jackson D, Seals, Douglas R
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326900/
https://ncbi.nlm.nih.gov/pubmed/24341314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12196
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