MicroRNA-Mediated In Vitro and In Vivo Direct Conversion of Astrocytes to Neuroblasts

BACKGROUND: The conversion of astrocytes to neuroblasts holds great promise for treatment of neurodegenerative and traumatic brain diseases. METHODOLOGY AND PRINCIPAL FINDINGS: Here we have shown that adult human astrocytes could be reprogrammed to neuroblasts by miR-302/367, both in vivo and in vit...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Ghasemi-Kasman, Maryam, Hajikaram, Maryam, Baharvand, Hossein, Javan, Mohammad
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451260/
https://ncbi.nlm.nih.gov/pubmed/26030913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127878
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