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In vivo reprogramming of astrocytes to neuroblasts in the adult brain
Adult differentiated cells can be reprogrammed into pluripotent stem cells or lineage-restricted proliferating precursors in culture; however, this has not been demonstrated in vivo. Here, we show that the single transcription factor SOX2 is sufficient to reprogram resident astrocytes into prolifera...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867822/ https://ncbi.nlm.nih.gov/pubmed/24056302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2843 |
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