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Detecting functional changes with [(18)F]FAZA in a renal cell carcinoma mouse model following sunitinib therapy

BACKGROUND: The multitargeting tyrosine kinase inhibitor (TKI) sunitinib is currently the first-line drug therapy for metastasizing renal cell carcinoma (RCC). TKIs have profound effects on tumor angiogenesis, leading to modifications of the tumor microenvironment. The goal of this study was to dete...

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Foilsithe in:EJNMMI Res
Main Authors: Chapman, David W, Jans, Hans-Sonke, Ma, Ivy, Mercer, John R, Wiebe, Leonard I, Wuest, Melinda, Moore, Ronald B
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451188/
https://ncbi.nlm.nih.gov/pubmed/26116107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0027-5
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