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Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer

6-Deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF) is a promising PET radiotracer for imaging GLUT5 in breast cancer. The present work describes GMP synthesis of 6-[(18)F]FDF in an automated synthesis unit (ASU) and dosimetry calculations to determine radiation doses in humans. GMP synthesis and dosi...

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Detalhes bibliográficos
Main Authors: Bouvet, Vincent, Jans, Hans S, Wuest, Melinda, Soueidan, Olivier-Mohamad, Mercer, John, McEwan, Alexander JB, West, Frederick G, Cheeseman, Chris I, Wuest, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999405/
https://ncbi.nlm.nih.gov/pubmed/24795839
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