Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation

Catalytic properties and cellular effects of the glutathione peroxidase (GPx)-mimetic compound PhSeZnCl or its d,l-lactide polymer microencapsulation form (M-PhSeZnCl) were investigated and compared with the prototypical Se-organic compounds ebselen and diselenide (PhSe)(2). PhSeZnCl was confirmed t...

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Bibliografiske detaljer
Udgivet i:Free Radic Biol Med
Main Authors: Bartolini, D., Piroddi, M., Tidei, C., Giovagnoli, S., Pietrella, D., Manevich, Y., Tew, K.D., Giustarini, D., Rossi, R., Townsend, D.M., Santi, C., Galli, F.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451065/
https://ncbi.nlm.nih.gov/pubmed/25452145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.10.008
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