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Using Genome-Scale Models to Predict Biological Capabilities

Constraint-based reconstruction and analysis (COBRA) methods at the genome-scale have been under development since the first whole genome sequences appeared in the mid-1990s. A few years ago this approach began to demonstrate the ability to predict a range of cellular functions including cellular gr...

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Publicat a:Cell
Autors principals: O’Brien, Edward J., Monk, Jonathan M., Palsson, Bernhard O.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451052/
https://ncbi.nlm.nih.gov/pubmed/26000478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.019
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