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Differential Chromosome Conformations as Hallmarks of Cellular Identity Revealed by Mathematical Polymer Modeling

Inherently dynamic, chromosomes adopt many different conformations in response to DNA metabolism. Models of chromosome organization in the yeast nucleus obtained from genome-wide chromosome conformation data or biophysical simulations provide important insights into the average behavior but fail to...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Lassadi, Imen, Kamgoué, Alain, Goiffon, Isabelle, Tanguy-le-Gac, Nicolas, Bystricky, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451008/
https://ncbi.nlm.nih.gov/pubmed/26030148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004306
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