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Differentiation of Human Ligamentum Flavum Stem Cells Toward Nucleus Pulposus-Like Cells Induced by Coculture System and Hypoxia

STUDY DESIGN. Human ligamentum flavum (LF)-derived stem cells (LFSCs) and nucleus pulposus cells (NPCs) were cocultured under normoxia or hypoxia. OBJECTIVE. To isolate and identify human LFSCs and determine whether they can differentiate into NPCs when cocultured with NPCs under hypoxia. SUMMARY OF...

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Bibliographic Details
Published in:Spine (Phila Pa 1976)
Main Authors: Han, Xiao-Bo, Zhang, Yan-Ling, Li, Hai-Yin, Chen, Bin, Chang, Xian, Zhang, Wei, Yang, Kuang, Zhou, Yue, Li, Chang-Qing
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450897/
https://ncbi.nlm.nih.gov/pubmed/25785962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0000000000000882
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