Functional Invariant NKT Cells in Pig Lungs Regulate the Airway Hyperreactivity: A Potential Animal Model

Important roles played by invariant natural killer T (iNKT) cells in asthma pathogenesis have been demonstrated. We identified functional iNKT cells and CD1d molecules in pig lungs. Pig iNKT cells cultured in the presence of α-GalCer proliferated and secreted Th1 and Th2 cytokines. Like in other ani...

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Detalhes bibliográficos
Publicado no:J Clin Immunol
Main Authors: Renukaradhya, Gourapura J., Manickam, Cordelia, Khatri, Mahesh, Rauf, Abdul, Li, Xiangming, Tsuji, Moriya, Rajashekara, Gireesh, Dwivedi, Varun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450678/
https://ncbi.nlm.nih.gov/pubmed/21042929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9476-4
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