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Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses
V-domain immunoglobulin suppressor of T-cell activation (VISTA) is a negative immune-checkpoint protein that suppresses T-cell responses. To determine whether VISTA synergizes with another immune-checkpoint, programmed death 1 (PD-1), this study characterizes the immune responses in VISTA-deficient,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4450438/ https://ncbi.nlm.nih.gov/pubmed/25964334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420370112 |
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