Rate, spectrum, and evolutionary dynamics of spontaneous epimutations

Stochastic changes in cytosine methylation are a source of heritable epigenetic and phenotypic diversity in plants. Using the model plant Arabidopsis thaliana, we derive robust estimates of the rate at which methylation is spontaneously gained (forward epimutation) or lost (backward epimutation) at...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: van der Graaf, Adriaan, Wardenaar, René, Neumann, Drexel A., Taudt, Aaron, Shaw, Ruth G., Jansen, Ritsert C., Schmitz, Robert J., Colomé-Tatché, Maria, Johannes, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450394/
https://ncbi.nlm.nih.gov/pubmed/25964364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424254112
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