Rate, spectrum, and evolutionary dynamics of spontaneous epimutations

Stochastic changes in cytosine methylation are a source of heritable epigenetic and phenotypic diversity in plants. Using the model plant Arabidopsis thaliana, we derive robust estimates of the rate at which methylation is spontaneously gained (forward epimutation) or lost (backward epimutation) at...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: van der Graaf, Adriaan, Wardenaar, René, Neumann, Drexel A., Taudt, Aaron, Shaw, Ruth G., Jansen, Ritsert C., Schmitz, Robert J., Colomé-Tatché, Maria, Johannes, Frank
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450394/
https://ncbi.nlm.nih.gov/pubmed/25964364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424254112
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