Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype

Diabetic foot ulceration is a major complication of diabetes. Substance P (SP) is involved in wound healing, but its effect in diabetic skin wounds is unclear. We examined the effect of exogenous SP delivery on diabetic mouse and rabbit wounds. We also studied the impact of deficiency in SP or its r...

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Detalles Bibliográficos
Publicado en:Am J Pathol
Main Authors: Leal, Ermelindo C., Carvalho, Eugénia, Tellechea, Ana, Kafanas, Antonios, Tecilazich, Francesco, Kearney, Cathal, Kuchibhotla, Sarada, Auster, Michael E., Kokkotou, Efi, Mooney, David J., LoGerfo, Frank W., Pradhan-Nabzdyk, Leena, Veves, Aristidis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450333/
https://ncbi.nlm.nih.gov/pubmed/25871534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.02.011
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