Development of In Vitro-In Vivo Correlation/Relationship Modeling Approaches for Immediate Release Formulations Using Compartmental Dynamic Dissolution Data from “Golem”: A Novel Apparatus

Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus, simulating stomach and small intestine. A universal dissolution method was employed which simulated the physiology of human gastrointestinal tract, i...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Čulen, Martin, Tuszyński, Paweł K., Polak, Sebastian, Jachowicz, Renata, Mendyk, Aleksander, Dohnal, Jiří
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450231/
https://ncbi.nlm.nih.gov/pubmed/26120580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/328628
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