From Heuristic to Mathematical Modeling of Drugs Dissolution Profiles: Application of Artificial Neural Networks and Genetic Programming

The purpose of this work was to develop a mathematical model of the drug dissolution (Q) from the solid lipid extrudates based on the empirical approach. Artificial neural networks (ANNs) and genetic programming (GP) tools were used. Sensitivity analysis of ANNs provided reduction of the original in...

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Publicat a:Comput Math Methods Med
Autors principals: Mendyk, Aleksander, Güres, Sinan, Jachowicz, Renata, Szlęk, Jakub, Polak, Sebastian, Wiśniowska, Barbara, Kleinebudde, Peter
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460208/
https://ncbi.nlm.nih.gov/pubmed/26101544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/863874
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