Cytoplasmic Actin Is an Extracellular Insect Immune Factor which Is Secreted upon Immune Challenge and Mediates Phagocytosis and Direct Killing of Bacteria, and Is a Plasmodium Antagonist

Actin is a highly versatile, abundant, and conserved protein, with functions in a variety of intracellular processes. Here, we describe a novel role for insect cytoplasmic actin as an extracellular pathogen recognition factor that mediates antibacterial defense. Insect actins are secreted from cells...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Sandiford, Simone L., Dong, Yuemei, Pike, Andrew, Blumberg, Benjamin J., Bahia, Ana C., Dimopoulos, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450071/
https://ncbi.nlm.nih.gov/pubmed/25658622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004631
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