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Cytoplasmic Actin Is an Extracellular Insect Immune Factor which Is Secreted upon Immune Challenge and Mediates Phagocytosis and Direct Killing of Bacteria, and Is a Plasmodium Antagonist

Actin is a highly versatile, abundant, and conserved protein, with functions in a variety of intracellular processes. Here, we describe a novel role for insect cytoplasmic actin as an extracellular pathogen recognition factor that mediates antibacterial defense. Insect actins are secreted from cells...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sandiford, Simone L., Dong, Yuemei, Pike, Andrew, Blumberg, Benjamin J., Bahia, Ana C., Dimopoulos, George
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450071/
https://ncbi.nlm.nih.gov/pubmed/25658622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004631
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