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Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

Plasmacytoid dendritic cells (pDCs) were initially considered as critical for innate immunity to viruses. However, our group has shown that pDCs bind to and inhibit the growth of Aspergillus fumigatus hyphae and that depletion of pDCs renders mice hypersusceptible to experimental aspergillosis. In t...

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Vydáno v:PLoS Pathog
Hlavní autoři: Loures, Flávio V., Röhm, Marc, Lee, Chrono K., Santos, Evelyn, Wang, Jennifer P., Specht, Charles A., Calich, Vera L. G., Urban, Constantin F., Levitz, Stuart M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450068/
https://ncbi.nlm.nih.gov/pubmed/25659141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004643
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