In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria

Dendritic cells (DCs) are phagocytes that are highly specialized for antigen presentation. Heterogeneous populations of macrophages and DCs form a phagocyte network inside the red pulp (RP) of the spleen, which is a major site for the control of blood-borne infections such as malaria. However, the d...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Borges da Silva, Henrique, Fonseca, Raíssa, Cassado, Alexandra dos Anjos, Machado de Salles, Érika, de Menezes, Maria Nogueira, Langhorne, Jean, Perez, Katia Regina, Cuccovia, Iolanda Midea, Ryffel, Bernhard, Barreto, Vasco M., Marinho, Cláudio Romero Farias, Boscardin, Silvia Beatriz, Álvarez, José Maria, D’Império-Lima, Maria Regina, Tadokoro, Carlos Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450059/
https://ncbi.nlm.nih.gov/pubmed/25658925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004598
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