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Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells

Calcineurin inhibitors (CNI), used frequently in solid organ transplant patients, are known to inhibit T cell proliferation, but their effect on humoral immunity is far less studied. Total and naive B cells from healthy adult donors were cultured in immunoglobulin (Ig)A- or IgG/IgE-promoting conditi...

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Detaylı Bibliyografya
Yayımlandı:Clin Exp Immunol
Asıl Yazarlar: De Bruyne, R, Bogaert, D, De Ruyck, N, Lambrecht, B N, Van Winckel, M, Gevaert, P, Dullaers, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449782/
https://ncbi.nlm.nih.gov/pubmed/25682989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12604
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