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Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells
Calcineurin inhibitors (CNI), used frequently in solid organ transplant patients, are known to inhibit T cell proliferation, but their effect on humoral immunity is far less studied. Total and naive B cells from healthy adult donors were cultured in immunoglobulin (Ig)A- or IgG/IgE-promoting conditi...
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| Publicado no: | Clin Exp Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449782/ https://ncbi.nlm.nih.gov/pubmed/25682989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12604 |
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