High interindividual variability in the CD4/CD8 T cell ratio and natalizumab concentration levels in the cerebrospinal fluid of patients with multiple sclerosis

Strongly decreased leucocyte counts and a reduced CD4/CD8 T cell ratio in the cerebrospinal fluid (CSF) of natalizumab (NZB)-treated multiple sclerosis (MS) patients may have implications on central nervous (CNS) immune surveillance. With regard to NZB-associated progressive multi-focal leucoencepha...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Harrer, A, Pilz, G, Wipfler, P, Oppermann, K, Sellner, J, Hitzl, W, Haschke-Becher, E, Afazel, S, Rispens, T, van der Kleij, D, Trinka, E, Kraus, J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Translation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449767/
https://ncbi.nlm.nih.gov/pubmed/25603898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12590
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