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Simultaneous Inference of Cancer Pathways and Tumor Progression from Cross-Sectional Mutation Data

Recent cancer sequencing studies provide a wealth of somatic mutation data from a large number of patients. One of the most intriguing and challenging questions arising from this data is to determine whether the temporal order of somatic mutations in a cancer follows any common progression. Since we...

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Publicat a:J Comput Biol
Autors principals: Raphael, Benjamin J., Vandin, Fabio
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449706/
https://ncbi.nlm.nih.gov/pubmed/25785493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0161
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