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Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity

Pancreatic β cells secrete insulin in order to maintain glucose homeostasis. However, various environmental stresses such as obesity have been shown to induce loss of secretory responsiveness in pancreatic β cells and pancreatic β cell apoptosis which can favor the development of type 2 diabetes (T2...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Med
Prif Awduron: Véret, Julien, Bellini, Lara, Giussani, Paola, Ng, Carl, Magnan, Christophe, Le Stunff, Hervé
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449690/
https://ncbi.nlm.nih.gov/pubmed/26237395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3020646
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