Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction

INTRODUCTION: The Tie2/angiopoietin (Tie2/Ang) and vascular endothelial growth factor receptor-ligand systems (VEGFR/VEGF) are recognized to play important roles in the regulation of microvascular endothelial function. Downregulation of these genes during sepsis has been implicated in the pathogenes...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Crit Care
Main Authors: Bomsztyk, Karol, Mar, Daniel, An, Dowon, Sharifian, Roya, Mikula, Michal, Gharib, Sina A, Altemeier, William A, Liles, W Conrad, Denisenko, Oleg
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449602/
https://ncbi.nlm.nih.gov/pubmed/25959381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0943-4
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki