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TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes

BACKGROUND: TANK-binding kinase (TBK1) is a non-canonical IκB kinase (IKK) involved in the regulation of type I interferons and of NF-κB signal transduction. It is activated by viral infections and inflammatory mediators and has therefore been associated with viral diseases, obesity, and rheumatoid...

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發表在:J Neuroinflammation
Main Authors: Möser, Christine V., Stephan, Heike, Altenrath, Katharina, Kynast, Katharina L., Russe, Otto Q., Olbrich, Katrin, Geisslinger, Gerd, Niederberger, Ellen
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449530/
https://ncbi.nlm.nih.gov/pubmed/25997745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0319-3
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