The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death

BACKGROUND: Activity of cyclooxygenase 2 (COX-2) in mouse oligodendrocyte precursor cells (OPCs) modulates vulnerability to excitotoxic challenge. The mechanism by which COX-2 renders OPCs more sensitive to excitotoxicity is not known. In the present study, we examined the hypothesis that OPC excito...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Carlson, Noel G., Bellamkonda, Satya, Schmidt, Linda, Redd, Jonathan, Huecksteadt, Thomas, Weber, Lauren Marissa, Davis, Ethan, Wood, Blair, Maruyama, Takayuki, Rose, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449524/
https://ncbi.nlm.nih.gov/pubmed/25997851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0323-7
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