Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death

BACKGROUND: We previously found that cyclooxygenase 2 (COX-2) was expressed in dying oligodendrocytes at the onset of demyelination in the Theiler's murine encephalomyelitis virus-induced demyelinating disease (TMEV-IDD) model of multiple sclerosis (MS) (Carlson et al. J.Neuroimmunology 2006, 1...

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Main Authors: Carlson, Noel G, Rojas, Monica A, Redd, Jonathan W, Tang, Philip, Wood, Blair, Hill, Kenneth E, Rose, John W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873241/
https://ncbi.nlm.nih.gov/pubmed/20388219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-25
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