The structure of CCT–Hsc70(NBD) suggests a mechanism for Hsp70 delivery of substrates to the chaperonin

Chaperones, a group of proteins that assist the folding of other proteins, seem to work in a coordinated manner. Two major chaperone families are heat-shock protein families Hsp60 and Hsp70. Here we show for the first time the formation of a stable complex between chaperonin-containing TCP-1 (CCT) a...

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Bibliografske podrobnosti
izdano v:Nat Struct Mol Biol
Main Authors: Cuéllar, Jorge, Martín-Benito, Jaime, Scheres, Sjors H W, Sousa, Rui, Moro, Fernando, López-Viñas, Eduardo, Gómez-Puertas, Paulino, Muga, Arturo, Carrascosa, José L, Valpuesta, José M
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449276/
https://ncbi.nlm.nih.gov/pubmed/18660820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1464
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