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Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT

The biogenesis of the cytoskeletal proteins actin and tubulin involves interaction of nascent chains of each of the two proteins with the oligomeric protein prefoldin (PFD) and their subsequent transfer to the cytosolic chaperonin CCT (chaperonin containing TCP-1). Here we show by electron microscop...

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Autores principales: Martín-Benito, Jaime, Boskovic, Jasminka, Gómez-Puertas, Paulino, Carrascosa, José L., Simons, C.Torrey, Lewis, Sally A., Bartolini, Francesca, Cowan, Nicholas J., Valpuesta, José M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC136944/
https://ncbi.nlm.nih.gov/pubmed/12456645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf640
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