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A nonmuscle myosin light chain kinase–dependent gene signature in peripheral blood mononuclear cells is linked to human asthma severity and exacerbation status

Abstract. Asthma is increasingly recognized as a heterogeneous disease influenced by complex genetic and environmental contributions. Myosin light chain kinase (MLCK; gene symbol, MYLK), especially the nonmuscle isoform nmMLCK, is a cytoskeleton protein known to be related to human asthma susceptibi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pulm Circ
Hauptverfasser: Zhou, Tong, Wang, Ting, Garcia, Joe G. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: University of Chicago Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449245/
https://ncbi.nlm.nih.gov/pubmed/26064459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/680357
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