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A nonmuscle myosin light chain kinase–dependent gene signature in peripheral blood mononuclear cells is linked to human asthma severity and exacerbation status

Abstract. Asthma is increasingly recognized as a heterogeneous disease influenced by complex genetic and environmental contributions. Myosin light chain kinase (MLCK; gene symbol, MYLK), especially the nonmuscle isoform nmMLCK, is a cytoskeleton protein known to be related to human asthma susceptibi...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Zhou, Tong, Wang, Ting, Garcia, Joe G. N.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449245/
https://ncbi.nlm.nih.gov/pubmed/26064459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/680357
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