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High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity

High-fat diet (HFD)-induced obesity is associated with insulin resistance, which may affect brain synaptic plasticity through impairment of insulin-sensitive processes underlying neuronal survival, learning, and memory. The experimental model consisted of 3 month-old C57BL/6J mice fed either a norma...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Liu, Zhigang, Patil, Ishan Y., Jiang, Tianyi, Sancheti, Harsh, Walsh, John P., Stiles, Bangyan L., Yin, Fei, Cadenas, Enrique
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449222/
https://ncbi.nlm.nih.gov/pubmed/26023930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128274
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