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Structural Dynamics of the Cereblon Ligand Binding Domain
Cereblon, a primary target of thalidomide and its derivatives, has been characterized structurally from both bacteria and animals. Especially well studied is the thalidomide binding domain, CULT, which shows an invariable structure across different organisms and in complex with different ligands. He...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449219/ https://ncbi.nlm.nih.gov/pubmed/26024445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128342 |
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