A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2

Drugs currently used for treating Parkinson's disease patients provide symptomatic relief without altering the neurodegenerative process. Our aim was to examine the possibility of using DJ-1 (PARK7), as a novel therapeutic target for Parkinson's disease. We designed a short peptide, named...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lev, Nirit, Barhum, Yael, Ben-Zur, Tali, Aharony, Israel, Trifonov, Lena, Regev, Noa, Melamed, Eldad, Gruzman, Arie, Offen, Daniel
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449207/
https://ncbi.nlm.nih.gov/pubmed/26024237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127549
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