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A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2

Drugs currently used for treating Parkinson's disease patients provide symptomatic relief without altering the neurodegenerative process. Our aim was to examine the possibility of using DJ-1 (PARK7), as a novel therapeutic target for Parkinson's disease. We designed a short peptide, named...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lev, Nirit, Barhum, Yael, Ben-Zur, Tali, Aharony, Israel, Trifonov, Lena, Regev, Noa, Melamed, Eldad, Gruzman, Arie, Offen, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449207/
https://ncbi.nlm.nih.gov/pubmed/26024237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127549
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