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Mechanism of Testosterone Deficiency in the Transgenic Sickle Cell Mouse

Testosterone deficiency is associated with sickle cell disease (SCD), but its underlying mechanism is not known. We investigated the possible occurrence and mechanism of testosterone deficiency in a mouse model of human SCD. Transgenic sickle male mice (Sickle) exhibited decreased serum and intrates...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Musicki, Biljana, Zhang, Yuxi, Chen, Haolin, Brown, Terry R., Zirkin, Barry R., Burnett, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449127/
https://ncbi.nlm.nih.gov/pubmed/26023917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128694
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