LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of oral anti-diabetic agents that improve glycemic control by inhibiting SGLT2-mediated renal glucose reabsorption. Currently available agents increase urinary glucose excretion (UGE) to <50% of maximal values because they do not i...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Pharmacol Res Perspect
Hoofdauteurs: Powell, David R, Smith, Melinda G, Doree, Deon D, Harris, Angela L, Xiong, Wendy W, Mseeh, Faika, Wilson, Alan, Gopinathan, Suma, Diaz, Damaris, Goodwin, Nicole C, Harrison, Bryce, Strobel, Eric, Rawlins, David B, Carson, Ken, Zambrowicz, Brian, Ding, Zhi-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2015
Onderwerpen:
Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448982/
https://ncbi.nlm.nih.gov/pubmed/26038705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.129
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items