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Development of an inducible caspase-9 safety switch for pluripotent stem cell–based therapies
Induced pluripotent stem cell (iPSC) therapies offer a promising path for patient-specific regenerative medicine. However, tumor formation from residual undifferentiated iPSC or transformation of iPSC or their derivatives is a risk. Inclusion of a suicide gene is one approach to risk mitigation. We...
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| Publicat a: | Mol Ther Methods Clin Dev |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4448736/ https://ncbi.nlm.nih.gov/pubmed/26052521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.53 |
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