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Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress.

The stability of proteins that constitute the neurofibrillary tangles and senile plaques of Alzheimer disease suggests that they would be ideal substrates for nonenzymatic glycation, a process that occurs over long times, even at normal levels of glucose, ultimately resulting in the formation of adv...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yan, S D, Chen, X, Schmidt, A M, Brett, J, Godman, G, Zou, Y S, Scott, C W, Caputo, C, Frappier, T, Smith, M A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44487/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7787
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