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Gene Expression Analysis of Tumor Spheroids Reveals a Role for Suppressed DNA Mismatch Repair in Multicellular Resistance to Alkylating Agents

Drug resistance is a major obstacle in the successful treatment of cancer. Thus, elucidation of the mechanisms responsible is a critical first step in trying to prevent or delay such manifestations of resistance. In this regard, three-dimensional multicellular tumor cell spheroids are intrinsically...

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מידע ביבליוגרפי
Main Authors: Francia, Giulio, Man, Shan, Teicher, Beverly, Grasso, Luigi, Kerbel, Robert S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC444854/
https://ncbi.nlm.nih.gov/pubmed/15254249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6837-6849.2004
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