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A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells

The roles of myocardin-related transcription factor A (MRTF-A) and MRTF-B in vascular endothelial cells are not completely understood. Here, we found a novel regulatory mechanism for MRTF-A/B function. MRTF-A/B tend to accumulate in the nucleus in arterial endothelial cells in vivo and human aortic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hayashi, Ken’ichiro, Murai, Toshiyuki, Oikawa, Hiroki, Masuda, Tomoyuki, Kimura, Kazuhiro, Muehlich, Susanne, Prywes, Ron, Morita, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448521/
https://ncbi.nlm.nih.gov/pubmed/26024305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10627
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